Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPY2R | P49146 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498503 | 0.93 | MAPT (0.53) | GRM5MAPTNPY2RNPC1RAB9A | |
| SCHEMBL1955176 | 0.90 | MAPT (0.62) | GRM5MAPTNPY2RNPC1RAB9A | |
| SCHEMBL14898019 | 0.89 | MAPT (0.54) | GRM5MAPTNPC1RAB9AKMT2A | |
| SCHEMBL6465956 | 0.88 | NPY2R (0.54) | MAPTNPY2RNPC1RAB9AKMT2A | |
| SCHEMBL6510132 | 0.88 | NPY2R (0.52) | GRM5MAPTNPY2RNPC1RAB9A | |
| SCHEMBL8306382 | 0.87 | MAPT (0.50) | GRM5MAPTNPY2RNPC1RAB9A | |
| SCHEMBL30771563 | 0.87 | NPC1 (0.61) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL2152084 | 0.87 | NPC1 (0.61) | MAPTNPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL14861923 | 0.85 | NPC1 (0.49) | GRM5MAPTNPY2RNPC1RAB9A | |
| SCHEMBL18396796 | 0.85 | MAPT (0.48) | GRM5MAPTNPY2RNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051933-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF 4-(4-BENZYLOXY-CARBONYLAMINO-2-FLUOROPHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, A KEY INTERMEDIATE FOR OXAZOLIDINONE ANTIMICROBIALS AND COMPOUNDS PREPARED THEREBY | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-09 | — | — | WO | claimed |
| WO-2005051933-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF 4-(4-BENZYLOXY-CARBONYLAMINO-2-FLUOROPHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, A KEY INTERMEDIATE FOR OXAZOLIDINONE ANTIMICROBIALS AND COMPOUNDS PREPARED THEREBY | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-09 | — | — | WO | disclosed |