Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498503 | 0.91 | MAPT (0.53) | NPY2RMAPTNPC1ALDH1A1TSHR | |
| SCHEMBL2449157 | 0.89 | BACE1 (0.50) | BACE1KMT2AMEN1P2RX7NAMPT | |
| SCHEMBL13532958 | 0.88 | BACE1 (0.52) | NPY2RBACE1LMNAKMT2AMEN1 | |
| SCHEMBL2090454 | 0.88 | MEN1 (0.45) | NPY2RBACE1MAPTNPC1GRM5 | |
| SCHEMBL6509573 | 0.88 | GRM5 (0.53) | NPY2RMAPTNPC1ALDH1A1TSHR | |
| SCHEMBL8250825 | 0.87 | L3MBTL1 (0.59) | NPY2RMAPTNPC1ALDH1A1TSHR | |
| SCHEMBL30063444 | 0.87 | L3MBTL1 (0.59) | NPY2RMAPTNPC1ALDH1A1TSHR | |
| SCHEMBL10151446 | 0.87 | MAPT (0.46) | NPY2RBACE1MAPTNPC1GRM5 | |
| SCHEMBL27586529 | 0.86 | NPY2R (0.46) | NPY2RMAPTNPC1ALDH1A1TSHR | |
| SCHEMBL7846281 | 0.86 | F13A1 (0.53) | NPY2RMAPTNPC1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101781293-B | Antibacterial compound, preparation method and application thereof | SHENYANG J & HEALTH PHARMACEUTICAL CO LTD | 2012-07-18 | — | — | CN | disclosed |
| CN-101781293-A | Antibacterial compound, preparation method and application thereof | BENXI RUISHENG PHARMACEUTICAL | 2010-07-21 | — | — | CN | disclosed |
| US-20070167414-A1 | Novel antibacterial agents | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2007-07-19 | — | — | US | disclosed |
| US-20070167414-A1 | Novel antibacterial agents | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2007-07-19 | — | — | US | disclosed |
| US-7217726-B2 | Antibacterial agents | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2007-05-15 | — | — | US | disclosed |
| US-7217726-B2 | Antibacterial agents | ORCHID CHEMICALS & PHARMACEUTICALS LIMITED (IN) | 2007-05-15 | — | — | US | disclosed |
| WO-2005051933-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF 4-(4-BENZYLOXY-CARBONYLAMINO-2-FLUOROPHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, A KEY INTERMEDIATE FOR OXAZOLIDINONE ANTIMICROBIALS AND COMPOUNDS PREPARED THEREBY | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-09 | — | — | WO | disclosed |
| WO-2005051933-A1 | AN IMPROVED PROCESS FOR THE SYNTHESIS OF 4-(4-BENZYLOXY-CARBONYLAMINO-2-FLUOROPHENYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER, A KEY INTERMEDIATE FOR OXAZOLIDINONE ANTIMICROBIALS AND COMPOUNDS PREPARED THEREBY | RANBAXY LABORATORIES LIMITED (IN) | 2005-06-09 | — | — | WO | disclosed |
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | LABORATORIOS VITA, S.A. (ES) | 2004-07-29 | — | — | US | disclosed |
| EP-1401834-A1 | NEW DERIVATIVES OF OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | LABORATORIOS VITA, S.A. (ES) | 2004-03-31 | — | — | EP | disclosed |
| WO-2003002560-A1 | NEW DERIVATIVES OF OXAZOLIDINONES AS ANTIBACTERIAL AGENTS | LABORATORIOS VITA, S.A. (ES) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167414-A1 | Novel antibacterial agents | TBCD, OXA1L, ALPI | NPY2R 3312/4885BACE1 2424/4885MAPT 48/4885 |
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | OXA1L, Q6ZSR9, PGC | NPY2R 3059/4885BACE1 4238/4885MAPT 3693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.