Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.78 |
| ▸ | MAPT | P10636 | 11/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.78 |
| ▸ | GAA | P10253 | 6/20 | 0.77 |
| ▸ | HPGD | P15428 | 4/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | ACHE | P22303 | 1/20 | 0.75 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.71 |
| ▸ | NCF1 | P14598 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5910282 | 0.88 | KMT2A (1.00) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL26723750 | 0.87 | KDM4E (1.00) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL19051441 | 0.86 | KDM4E (1.00) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL6509340 | 0.86 | KDM4E (0.70) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL29351521 | 0.86 | KDM4E (1.00) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14975993 | 0.86 | KDM4E (1.00) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL5910684 | 0.84 | KMT2A (0.72) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL4821642 | 0.83 | NCF1 (1.00) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| SCHEMBL3971448 | 0.80 | KMT2A (0.67) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL3971486 | 0.79 | KMT2A (0.65) | KMT2AKDM4EMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005087742-A1 | METABOLIC KINASE MODULATORS AND METHODS OF USE AS PESTICIDES | EXELIXIS, INC. (US) | 2005-09-22 | — | — | WO | claimed |
| WO-2005087742-A1 | METABOLIC KINASE MODULATORS AND METHODS OF USE AS PESTICIDES | EXELIXIS, INC. (US) | 2005-09-22 | — | — | WO | disclosed |