Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509803 | 0.89 | SMN1; SMN2 (0.50) | SMN1; SMN2GLABACE1ATMCSNK2A1 | |
| SCHEMBL6508657 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2GLABACE1ATMCSNK2A1 | |
| SCHEMBL6507837 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2GLABACE1ATMCSNK2A1 | |
| SCHEMBL6509412 | 0.77 | DRD2 (0.35) | PPARGDRD2DRD4DRD3 | |
| SCHEMBL9399818 | 0.74 | SMN1; SMN2 (0.77) | SMN1; SMN2GLABACE1ATMCSNK2A1 | |
| SCHEMBL5146702 | 0.70 | SMN1; SMN2 (0.71) | SMN1; SMN2GLABACE1ATMCSNK2A1 | |
| SCHEMBL6510643 | 0.70 | SMN1; SMN2 (0.45) | SMN1; SMN2GLABACE1ATMCSNK2A1 | |
| SCHEMBL9398842 | 0.70 | SMN1; SMN2 (0.70) | SMN1; SMN2GLABACE1ATMCSNK2A1 | |
| SCHEMBL15189516 | 0.70 | SMN1; SMN2 (0.69) | SMN1; SMN2GLABACE1ATMCSNK2A1 | |
| SCHEMBL5144000 | 0.69 | SMN1; SMN2 (0.54) | SMN1; SMN2GLABACE1ATMCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005108374-A1 | INSECTICIDAL DIAZOLE AND TRIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2005-11-17 | — | — | WO | disclosed |