Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13825175 | 1.00 | KCNH2 (0.62) | KCNH2L3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL14289856 | 0.95 | L3MBTL1 (0.69) | KCNH2L3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL11995967 | 0.93 | L3MBTL1 (0.72) | KCNH2L3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL4069939 | 0.89 | TDP1 (0.64) | L3MBTL1TDP1DRD2HRH3HRH4 | |
| SCHEMBL17914305 | 0.87 | KCNH2 (0.58) | KCNH2L3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL20234653 | 0.86 | KCNH2 (0.58) | KCNH2L3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL28506052 | 0.86 | KCNH2 (0.57) | KCNH2L3MBTL1TDP1DRD2DRD4 | |
| SCHEMBL3438748 | 0.85 | TDP1 (0.60) | L3MBTL1TDP1DRD2HRH3HRH4 | |
| SCHEMBL9331681 | 0.84 | TACR1 (0.53) | KCNH2L3MBTL1TDP1HRH3HRH4 | |
| SCHEMBL1839074 | 0.84 | TDP1 (0.59) | L3MBTL1TDP1HRH3HRH4IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100329-A1 | NOVEL PROTECTING REAGENTS, PROTECTING GROUPS AND METHODS OF FORMING AND USING THE SAME | THE UNIVERSITY OF MISSISSIPI (US) | 2005-10-27 | — | — | WO | disclosed |