Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 16/20 | 0.72 |
| ▸ | MAOB | P27338 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21999062 | 1.00 | MAOA (0.72) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL3328501 | 0.90 | CYP3A4 (0.79) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL3328495 | 0.90 | CYP3A4 (0.79) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL3328493 | 0.90 | CYP3A4 (0.79) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL11983302 | 0.89 | MAOA (0.73) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL4168836 | 0.88 | MAOA (0.71) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL2849327 | 0.88 | MAOA (0.71) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL1033575 | 0.88 | MAOA (0.71) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL18770272 | 0.88 | MAOA (0.71) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL3195535 | 0.88 | MAOA (0.71) | MAOAMAOBCYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042523-A1 | A NOVEL OXAZOLIDINONE DERIVATIVE AND MANUFACTURING PROCESS THEREOF | IL-DONG PHARM. CO., LTD. (KR) | 2005-05-12 | — | — | WO | disclosed |