Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9341487 | 0.93 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1RXRARXRBPLK1 | |
| SCHEMBL14218108 | 0.83 | RARB (0.49) | SMN1; SMN2ALDH1A1PLK1TP53LPL | |
| SCHEMBL5033205 | 0.78 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1RXRARXRBPLK1 | |
| SCHEMBL1622617 | 0.78 | KMT2A (0.61) | SMN1; SMN2ALDH1A1RXRARXRBPLK1 | |
| SCHEMBL15214998 | 0.78 | KMT2A (0.61) | SMN1; SMN2ALDH1A1RXRARXRBPLK1 | |
| SCHEMBL1702558 | 0.78 | TP53 (0.56) | SMN1; SMN2ALDH1A1EGFRTP53METAP2 | |
| SCHEMBL2776957 | 0.78 | TP53 (0.56) | SMN1; SMN2ALDH1A1EGFRTP53METAP2 | |
| SCHEMBL6514251 | 0.77 | KMT2A (0.58) | SMN1; SMN2ALDH1A1PLK1TP53TDP1 | |
| SCHEMBL9420265 | 0.76 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1RXRARXRBPLK1 | |
| SCHEMBL9338315 | 0.76 | PLK1 (0.52) | SMN1; SMN2ALDH1A1PLK1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050101063-A1 | Three-terminal field-controlled molecular devices | TOUR JAMES M (US) | 2005-05-12 | — | — | US | disclosed |
| WO-2002035580-A2 | THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES | MOLECULAR ELECTRONICS CORPORATION (US) | 2002-05-02 | — | — | WO | disclosed |