Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 20/20 | 0.50 |
| ▸ | PPARA | Q07869 | 16/20 | 0.50 |
| ▸ | PPARD | Q03181 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510502 | 1.00 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL6505006 | 0.92 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL6505003 | 0.92 | PPARG (0.58) | PPARGPPARAPPARD | |
| SCHEMBL6503040 | 0.82 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6503037 | 0.82 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6506595 | 0.76 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL6506592 | 0.76 | PPARG (0.52) | PPARGPPARAPPARD | |
| SCHEMBL6507933 | 0.75 | ESR1 (0.50) | PPARGPPARAPPARD | |
| SCHEMBL6510040 | 0.75 | ESR1 (0.50) | PPARGPPARAPPARD | |
| SCHEMBL6508944 | 0.74 | PPARG (0.59) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | claimed |
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |