Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.52 |
| ▸ | PPARA | Q07869 | 12/20 | 0.52 |
| ▸ | PPARD | Q03181 | 4/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6506595 | 1.00 | PPARG (0.52) | PPARGPPARAPPARDLTA4HITGB3 | |
| SCHEMBL6504116 | 0.84 | MIF (0.50) | PPARGPPARAPPARDLTA4H | |
| SCHEMBL6504111 | 0.84 | MIF (0.50) | PPARGPPARAPPARDLTA4H | |
| SCHEMBL6503040 | 0.78 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6503037 | 0.78 | PPARG (0.51) | PPARGPPARAPPARD | |
| SCHEMBL6532483 | 0.77 | PPARG (0.43) | PPARGPPARAPPARDLTA4H | |
| SCHEMBL6532478 | 0.77 | PPARG (0.43) | PPARGPPARAPPARDLTA4H | |
| SCHEMBL7033327 | 0.76 | PPARG (0.67) | PPARGPPARAPPARDLTA4HITGB3 | |
| SCHEMBL6510502 | 0.76 | PPARG (0.50) | PPARGPPARAPPARD | |
| SCHEMBL6510499 | 0.76 | PPARG (0.50) | PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |