Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 5/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | DAO | P14920 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | DDO | Q99489 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7841259 | 0.87 | KDR (0.51) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL973208 | 0.85 | KDR (0.50) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL7094486 | 0.85 | KDR (0.50) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL3735366 | 0.78 | KDR (0.56) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL3234457 | 0.75 | KDR (0.56) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL354610 | 0.75 | KDR (0.56) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL71078 | 0.75 | KDR (0.56) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL9690611 | 0.75 | KDR (0.56) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL3859295 | 0.75 | KDR (0.56) | KDRCHEK1FLT3KDM4EMAPT | |
| SCHEMBL7088772 | 0.75 | KDR (0.56) | KDRCHEK1FLT3KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063760-A1 | C-8 LINKED PYRROLO[2,1-c][1,4]BENZODIAZEPINE-ACRIDONE/ACRIDINE HYBRIDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | disclosed |