SCHEMBL7094486

SCHEMBL7094486

O=C(Cl)c1ccc2[nH]c3ccccc3cc-2c1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDR P35968 5/20 0.50
CHEK1 O14757 1/20 0.50
FLT3 P36888 1/20 0.42
KDM4E B2RXH2 5/20 0.41
MAPT P10636 4/20 0.41
HPGD P15428 4/20 0.41
DAO P14920 2/20 0.41
HSD17B10 Q99714 2/20 0.41
SRD5A2 P31213 1/20 0.41
DDO Q99489 1/20 0.41
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CASP3 P42574 1/20 0.40
SENP8 Q96LD8 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7841259 0.87 KDR (0.51) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL973208 0.85 KDR (0.50) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL6510708 0.85 KDR (0.50) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL195409 0.78 KDR (0.56) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL3735366 0.78 KDR (0.56) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL11365957 0.77 KDR (0.54) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL9690611 0.75 KDR (0.56) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL3234457 0.75 KDR (0.56) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL354610 0.75 KDR (0.56) KDRCHEK1FLT3KDM4EMAPT
SCHEMBL71078 0.75 KDR (0.56) KDRCHEK1FLT3KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0763580-B1 Aqueous type pigment dispersing agent, composition containing the same and aqueous pigment dispersion TOYO INK MFG CO (JP) 2003-08-13 EP disclosed
US-5854323-A Pigment dispersing agent, composition containing the same, and aqueous pigment dispersion TOYO INK MANUFACTURING CO., LTD. (JP) 1998-12-29 US disclosed
EP-0763580-A2 Aqueous type pigment dispersing agent, composition containing the same and aqueous pigment dispersion TOYO INK MANUFACTURING CO., LTD. (JP) 1997-03-19 EP disclosed
EP-0763378-A2 Non-aqueous type pigment dispersing agent, composition containing thereof, and non-aqueous pigment dispersion TOYO INK MANUFACTURING CO., LTD. (JP) 1997-03-19 EP disclosed