SCHEMBL6510973

SCHEMBL6510973

CCCCc1cccnc1[C]=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37
CASP3 P42574 1/20 0.37
RAB9A P51151 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
SENP8 Q96LD8 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
CTRC Q99895 1/20 0.37
FAAH O00519 7/20 0.35
KAT2B Q92831 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LIPG Q9Y5X9 1/20 0.35
PDE4A P27815 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6507690 0.95 TDP1 (0.41) L3MBTL1FAAHKAT2BTDP1LIPG
SCHEMBL6506893 0.89 GRM5 (0.42) L3MBTL1ALDH1A1HPGDNPSR1PDE4A
SCHEMBL6507278 0.83 GABRA1 (0.39) L3MBTL1ALDH1A1SMN1; SMN2NPSR1
SCHEMBL5233261 0.83 CYP11B1 (0.48) CYP3A4CYP2D6CYP2C9L3MBTL1NPC1
SCHEMBL7021136 0.82 NR1H2 (0.43) L3MBTL1TDP1LIPGTLR8
SCHEMBL7474245 0.80 DAGLA (0.33) FAAHDAGLA
SCHEMBL7470082 0.79 KDM4E (0.36) L3MBTL1NPC1ALDH1A1RAB9ASMN1; SMN2
SCHEMBL29057132 0.78 TDP1 (0.41) L3MBTL1KAT2BTDP1LIPGTLR8
SCHEMBL27764936 0.78 CYP11B1 (0.47) L3MBTL1NPC1ALDH1A1HPGDCASP3
SCHEMBL10982801 0.77 CYP11B1 (0.46) L3MBTL1NPC1ALDH1A1HPGDCASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005082892-A2 TRIAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM DR. REDDY'S LABORATORIES LTD. (IN) 2005-09-09 WO disclosed