SCHEMBL6511066

SCHEMBL6511066

Cc1cc(SC(F)(F)F)c(Cl)cc1NC(=O)NC(=O)c1c(F)cccc1Cl

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.52
MEN1 O00255 2/20 0.52
MAPT P10636 4/20 0.48
USP2 O75604 1/20 0.48
ALOX15 P16050 1/20 0.48
GAA P10253 7/20 0.47
TLR7 Q9NYK1 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.43
ATM Q13315 1/20 0.43
PPIA P62937 1/20 0.43
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
POLB P06746 1/20 0.42
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6509297 0.96 MEN1 (0.57) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6509500 0.94 KMT2A (0.49) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6507685 0.90 KMT2A (0.55) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6507227 0.90 KMT2A (0.48) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6509959 0.86 ATM (0.50) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6509567 0.86 ATM (0.50) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6511572 0.86 KMT2A (0.60) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6508027 0.85 KMT2A (0.49) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6508648 0.84 KMT2A (0.52) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL6507276 0.83 KMT2A (0.49) KMT2AMEN1MAPTUSP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100374427-C Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEM TAKEDA AGRO CO (JP) 2008-03-12 CN disclosed
CN-101108830-A Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEM TAKEDA AGRO CO (JP) 2008-01-23 CN disclosed
CN-101003517-A Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEM TAKEDA AGRO CO (JP) 2007-07-25 CN disclosed
CN-1649850-A Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEM TAKEDA AGRO CO (JP) 2005-08-03 CN disclosed
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-07-21 US disclosed
EP-1481972-A1 CYCLIC COMPOUND, PROCESS FOR PRODUCING THE SAME, AND PEST CONTROL AGENT Sumitomo Chemical Takeda Agro Company, Limited (JP) 2004-12-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050159599-A1 Cyclic compound, process for producing the same, and pest control agent CNPY2, CNPY3, HAX1 KMT2A 1362/4885MEN1 2593/4885MAPT 4484/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.