⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188862 | 0.89 | — | — | |
| SCHEMBL2307623 | 0.78 | — | — | |
| SCHEMBL6373519 | 0.74 | — | — | |
| SCHEMBL278413 | 0.68 | — | — | |
| SCHEMBL3465341 | 0.67 | — | — | |
| SCHEMBL17839410 | 0.65 | — | — | |
| SCHEMBL14138851 | 0.63 | — | — | |
| SCHEMBL2281780 | 0.59 | — | — | |
| SCHEMBL991862 | 0.56 | — | — | |
| SCHEMBL13879644 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2025000782-A | REGIMENS OF ESTROGEN RECEPTOR ANTAGONISTS | オレマ ファーマシューティカルズ インク． | 2025-01-07 | — | — | JP | disclosed |
| US-20050032790-A1 | For example, 1-(2-Amino-4-chlorobenzoyl-D-phenylglycinyl)-4,4'-bispiperidine; for treatment of thrombosis, emphysema, cirrhosis; antiarthritic agents, anticancer agents, antihistamines | LIEBESCHUETZ JOHN WALTER (GB) | 2005-02-10 | — | — | US | disclosed |