Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509614 | 0.94 | PPARG (0.43) | PPARAPPARG | |
| SCHEMBL6511781 | 0.90 | PPARG (0.40) | PPARAPPARG | |
| SCHEMBL6511665 | 0.85 | PPARG (0.39) | PPARAPPARG | |
| SCHEMBL6278763 | 0.80 | PPARA (0.52) | PPARAPPARGCNR2 | |
| SCHEMBL6280585 | 0.79 | PPARG (0.45) | PPARAPPARG | |
| SCHEMBL6280589 | 0.79 | PPARG (0.45) | PPARAPPARG | |
| SCHEMBL6363745 | 0.78 | PPARG (0.37) | PPARAPPARG | |
| SCHEMBL6507722 | 0.77 | PPARG (0.39) | PPARAPPARG | |
| SCHEMBL6275505 | 0.76 | PPARA (0.50) | PPARAPPARG | |
| SCHEMBL6277698 | 0.74 | PPARG (0.43) | PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042509-A1 | 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS | ALLERGAN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |