Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370694 | 0.87 | — | — | |
| SCHEMBL5553709 | 0.87 | — | — | |
| SCHEMBL3186066 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL10822867 | 0.71 | CYP2D6 (0.34) | GABRR1 | |
| Trifluoroacetic Acid SCHEMBL3555663 | 0.71 | DPP8 (0.44) | DPP8DPP7DPP4 | |
| SCHEMBL27874873 | 0.70 | — | — | |
| Trifluoroacetic Acid SCHEMBL27637911 | 0.69 | DPP8 (0.40) | DPP8DPP7DPP4GABRR1 | |
| SCHEMBL20030568 | 0.68 | PIK3CD (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL611854 | 0.68 | TSHR (0.53) | DPP8DPP7DPP4 | |
| Trifluoroacetic Acid SCHEMBL28304481 | 0.68 | DPP8 (0.38) | DPP8DPP7DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005051380-A1 | SUBSTITUTED UREA-OCTAHYDROINDOLS AS ANTAGONISTS OF MELANIN CONCENTRATING HORMONE RECEPTOR 1 (MCH1R) | BIOVITRUM AB (SE) | 2005-06-09 | — | — | WO | claimed |