Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.45 |
| ▸ | PPARG | P37231 | 12/20 | 0.45 |
| ▸ | PPARD | Q03181 | 8/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512822 | 1.00 | PPARA (0.45) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL6509466 | 0.91 | PPARA (0.41) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL6512591 | 0.91 | PPARA (0.41) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL6513058 | 0.89 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6512166 | 0.89 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6511438 | 0.89 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6509482 | 0.89 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL6510038 | 0.89 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL3284481 | 0.88 | PPARA (0.43) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL6509616 | 0.85 | PPARA (0.49) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |