Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.41 |
| ▸ | PPARG | P37231 | 7/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509466 | 0.97 | PPARA (0.41) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL6512176 | 0.92 | PPARA (0.49) | PPARAPPARGPPARDFBP1 | |
| SCHEMBL6512822 | 0.91 | PPARA (0.45) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL6511690 | 0.91 | PPARA (0.45) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL6509616 | 0.90 | PPARA (0.49) | PPARAPPARGPPARDFBP1 | |
| SCHEMBL6513058 | 0.85 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6511438 | 0.85 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6512166 | 0.85 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL3284481 | 0.84 | PPARA (0.43) | PPARAPPARGTSHRABCB11CYP1A2 | |
| SCHEMBL3286019 | 0.84 | PPARA (0.38) | PPARAPPARGTSHRABCB11CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | claimed |