Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F13A1 | P00488 | 3/20 | 0.47 |
| ▸ | TGM2 | P21980 | 3/20 | 0.47 |
| ▸ | TGM1 | P22735 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR1B | P28222 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509011 | 0.86 | F10 (0.52) | MEN1KMT2ANPSR1NPC1RAB9A | |
| SCHEMBL6517565 | 0.86 | NPC1 (0.44) | HDAC1NPC1RAB9ASMN1; SMN2DPP4 | |
| SCHEMBL6513454 | 0.79 | MAPT (0.50) | F13A1TGM2TGM1MEN1KMT2A | |
| SCHEMBL19212175 | 0.79 | NPSR1 (0.52) | F13A1TGM2TGM1HDAC1MEN1 | |
| SCHEMBL13756987 | 0.79 | NPSR1 (0.52) | F13A1TGM2TGM1HDAC1MEN1 | |
| SCHEMBL31639673 | 0.78 | SMN1; SMN2 (0.51) | F13A1TGM2TGM1HDAC1MEN1 | |
| SCHEMBL1498503 | 0.78 | MAPT (0.53) | F13A1TGM2TGM1MEN1KMT2A | |
| SCHEMBL5945165 | 0.78 | MGAT2 (0.43) | HDAC1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL2449157 | 0.77 | BACE1 (0.50) | MEN1KMT2A | |
| SCHEMBL20722397 | 0.77 | MEN1 (0.52) | HDAC1MEN1KMT2ANPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005113520-A1 | SUBSTITUTED 2,3,5-TRIFLUORPHENYL OXAZOLIDINONES FOR USE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-12-01 | — | — | WO | disclosed |