Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6509011 | 0.87 | F10 (0.52) | NPC1RAB9AF10POLBMGLL | |
| SCHEMBL6512014 | 0.86 | F13A1 (0.47) | NPC1RAB9AF10HDAC1HDAC2 | |
| SCHEMBL4011941 | 0.86 | MGLL (0.48) | NPC1RAB9APOLBMGLLMAOB | |
| SCHEMBL23525572 | 0.82 | F10 (0.46) | NPC1RAB9AF10HDAC3HDAC1 | |
| SCHEMBL18396806 | 0.80 | MGLL (0.47) | NPC1RAB9APOLBMGLLMAOB | |
| SCHEMBL5945165 | 0.78 | MGAT2 (0.43) | NPC1RAB9AF10HDAC3HDAC1 | |
| SCHEMBL7037968 | 0.78 | MGLL (0.41) | NPC1RAB9APOLBMGLLMAOB | |
| SCHEMBL8306382 | 0.77 | MAPT (0.50) | NPC1RAB9APOLBMGLLMAOB | |
| SCHEMBL18787363 | 0.75 | MGLL (0.47) | NPC1RAB9APOLBMGLLALDH1A1 | |
| SCHEMBL18396765 | 0.74 | MAPT (0.47) | NPC1RAB9AMGLLMAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005113520-A1 | SUBSTITUTED 2,3,5-TRIFLUORPHENYL OXAZOLIDINONES FOR USE AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-12-01 | — | — | WO | disclosed |