Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.34 |
| ▸ | PGK1 | P00558 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2609819 | 0.87 | TSHR (0.44) | TSHRHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL28034496 | 0.87 | TSHR (0.44) | TSHRHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL8450876 | 0.87 | TSHR (0.44) | TSHRHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL27902962 | 0.87 | TSHR (0.44) | TSHRHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL16416384 | 0.87 | TSHR (0.44) | TSHRHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL22400187 | 0.77 | PTGDR2 (0.44) | TSHRHSD17B10ALDH1A1HPGDALOX5 | |
| SCHEMBL28959310 | 0.77 | NOS2 (0.50) | TSHRHSD17B10ALDH1A1HPGD | |
| SCHEMBL29467123 | 0.75 | TYR (0.39) | TSHRHSD17B10ALDH1A1HPGDTYR | |
| SCHEMBL18923563 | 0.75 | HSD17B10 (0.53) | TSHRHSD17B10ALDH1A1TP53CYP3A4 | |
| SCHEMBL24267634 | 0.73 | HSD17B10 (0.51) | TSHRHSD17B10ALDH1A1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105820-A2 | MACROCYCLIC CADMIUM COMPLEXES | UNIVERSITY OF EAST ANGLIA (GB) | 2005-11-10 | — | — | WO | disclosed |