Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 5/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 6/20 | 0.47 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6561292 | 0.88 | ITGB1 (0.56) | ITGB1ITGA4ITGB3ITGAVITGA2B | |
| SCHEMBL14799578 | 0.88 | ITGB1 (0.56) | ITGB1ITGA4ITGB3ITGAVITGA2B | |
| SCHEMBL6638467 | 0.84 | ITGB1 (0.63) | ITGB1ITGA4ITGB3ITGAVITGA2B | |
| SCHEMBL20715930 | 0.84 | ITGB3 (0.61) | ITGB1ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL27278646 | 0.82 | KLK5 (0.54) | ITGB1ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL15140552 | 0.82 | ITGB1 (0.48) | ITGB1ITGA4ITGB3ITGAVITGA2B | |
| SCHEMBL15140555 | 0.82 | ITGB1 (0.48) | ITGB1ITGA4ITGB3ITGAVITGA2B | |
| SCHEMBL19234613 | 0.81 | KLK5 (0.59) | ITGB1ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL22427549 | 0.81 | KLK5 (0.53) | ITGB1ITGB3ITGAVITGA2BITGB5 | |
| SCHEMBL27278632 | 0.81 | KLK5 (0.53) | ITGB1ITGB3ITGAVITGA2BITGB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6911451-B1 | Phenylalanine derivatives | CELLTECH R&D LIMITED (GB) | 2005-06-28 | — | — | US | disclosed |