Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 4/20 | 0.49 |
| ▸ | UGCG | Q16739 | 4/20 | 0.49 |
| ▸ | GBA2 | Q9HCG7 | 4/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AGXT | P21549 | 2/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21169170 | 1.00 | GBA1 (0.49) | GBA1UGCGGBA2ADRB2KCNH2 | |
| SCHEMBL9278188 | 0.98 | GBA1 (0.47) | GBA1UGCGGBA2ADRB2KCNH2 | |
| SCHEMBL12361733 | 0.92 | AGXT (0.47) | GBA1UGCGGBA2ADRB2KCNH2 | |
| SCHEMBL4025519 | 0.87 | UGCG (0.49) | GBA1UGCGGBA2ADRB2KCNH2 | |
| SCHEMBL1180203 | 0.84 | AGXT (0.50) | GBA1UGCGGBA2ADRB2KCNH2 | |
| SCHEMBL28451813 | 0.83 | AGXT (0.45) | GBA1UGCGGBA2ADRB2KCNH2 | |
| SCHEMBL19837706 | 0.83 | AGXT (0.45) | GBA1UGCGGBA2ADRB2KCNH2 | |
| SCHEMBL9233338 | 0.83 | TSHR (0.48) | TDP1L3MBTL1NPC1RAB9A | |
| SCHEMBL6551488 | 0.82 | L3MBTL1 (0.65) | GBA1UGCGGBA2TDP1L3MBTL1 | |
| SCHEMBL16614410 | 0.82 | L3MBTL1 (0.65) | GBA1UGCGGBA2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005100329-A1 | NOVEL PROTECTING REAGENTS, PROTECTING GROUPS AND METHODS OF FORMING AND USING THE SAME | THE UNIVERSITY OF MISSISSIPI (US) | 2005-10-27 | — | — | WO | disclosed |