Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | DCTPP1 | Q9H773 | 10/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | WEE1 | P30291 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520390 | 0.87 | ATM (0.36) | ATMDCTPP1PPARGTDP1ALDH1A1 | |
| SCHEMBL6515682 | 0.86 | ATM (0.53) | ATMMAPK1HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6520247 | 0.81 | ALDH1A1 (0.40) | DCTPP1TDP1ALDH1A1 | |
| SCHEMBL6514788 | 0.78 | ALDH1A1 (0.38) | DCTPP1PPARGSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL6514231 | 0.74 | ATM (0.50) | ATMPPARGMAPK1HTTSMN1; SMN2 | |
| SCHEMBL6514897 | 0.74 | MGAM (0.46) | ATMDCTPP1PPARGMAPK1HTT | |
| SCHEMBL6511599 | 0.73 | MGAM (0.42) | ATMDCTPP1PPARGSMN1; SMN2 | |
| SCHEMBL6514332 | 0.72 | — | — | |
| SCHEMBL6514335 | 0.72 | — | — | |
| SCHEMBL6513852 | 0.71 | MGAM (0.44) | DCTPP1PPARGHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | NATIONAL SCIENCE FOUNDATION | 2005-10-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050239767-A1 | Intermolecular SNAr of the heterocycle-activated nitro and fluoro groups-application in the synthesis of polyazamacrocyclic ligands | TECR, PAICS, DCXR | ATM 2834/4885DCTPP1 4167/4885PPARG 1801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.