Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL2486393 | 0.83 | ALDH1A1 (0.54) | ALDH1A1ALOX15MAPTHDAC8TDP1 | |
| SCHEMBL16230454 | 0.81 | ALDH1A1 (0.56) | ALDH1A1ALOX15MAPTHDAC8TDP1 | |
| SCHEMBL5172986 | 0.80 | ALDH1A1 (0.61) | ALDH1A1ALOX15MAPTHDAC8TDP1 | |
| SCHEMBL29033095 | 0.80 | NPC1 (0.50) | ALDH1A1MAPTCA12CA1CA2 | |
| SCHEMBL3039302 | 0.79 | AKR1C1 (0.53) | ALDH1A1ALOX15MAPTTDP1AKR1C3 | |
| SCHEMBL3039305 | 0.79 | AKR1C1 (0.53) | ALDH1A1ALOX15MAPTTDP1AKR1C3 | |
| SCHEMBL348321 | 0.79 | AKR1C1 (0.53) | ALDH1A1ALOX15MAPTTDP1AKR1C3 | |
| Phthalic Acid SCHEMBL27458631 | 0.77 | ALDH1A1 (0.78) | ALDH1A1ALOX15MAPTHDAC8TDP1 | |
| SCHEMBL9021562 | 0.77 | PRMT5 (0.37) | ALDH1A1TDP1FOLH1TSHR | |
| SCHEMBL9021554 | 0.77 | PRMT5 (0.37) | ALDH1A1TDP1FOLH1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560599-A1 | PRODRUGS BUILT AS MULTIPLE SELF-ELIMINATION-RELEASE SPACERS | Syntarga B.V. (NL) | 2005-08-10 | — | — | EP | disclosed |
| WO-2004043493-A1 | PRODRUGS BUILT AS MULTIPLE SELF-ELIMINATION-RELEASE SPACERS | SYNTARGA B.V. (NL) | 2004-05-27 | — | — | WO | disclosed |