Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6512404 | 1.00 | MGLL (0.46) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6511161 | 0.95 | MGLL (0.42) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6511164 | 0.95 | MGLL (0.42) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6508178 | 0.90 | MGLL (0.46) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6508181 | 0.90 | MGLL (0.46) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6511479 | 0.90 | MGLL (0.47) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6511478 | 0.90 | MGLL (0.47) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6511800 | 0.86 | MGLL (0.42) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6511798 | 0.86 | MGLL (0.42) | MGLLSMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL6512420 | 0.85 | MGLL (0.43) | MGLLSMN1; SMN2TP53MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005082900-A2 | OXAZOLIDINONE AMIDOXIMES AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2005-09-09 | — | — | WO | disclosed |