⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27581641 | 0.79 | EP300 (0.32) | — | |
| SCHEMBL19705967 | 0.73 | — | — | |
| SCHEMBL6510859 | 0.72 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL887517 | 0.71 | — | — | |
| SCHEMBL28274631 | 0.70 | ALB (0.30) | — | |
| SCHEMBL27997587 | 0.68 | EP300 (0.32) | — | |
| SCHEMBL28004770 | 0.66 | FGFR1 (0.40) | — | |
| SCHEMBL19259069 | 0.63 | FGFR1 (0.30) | — | |
| SCHEMBL19008258 | 0.59 | ADK (0.45) | — | |
| SCHEMBL7639592 | 0.59 | ALB (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059627-A1 | CRF2 ligands in combination therapy | HO SIEW PENG (US) | 2005-03-17 | — | — | US | claimed |
| US-20020035083-A1 | CRF2 ligands in combination therapy | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-03-21 | — | — | US | claimed |
| US-20050059627-A1 | CRF2 ligands in combination therapy | HO SIEW PENG (US) | 2005-03-17 | — | — | US | disclosed |
| US-20020035083-A1 | CRF2 ligands in combination therapy | BRISTOL-MYERS SQUIBB PHARMA COMPANY | 2002-03-21 | — | — | US | disclosed |