Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.47 |
| ▸ | PPARG | P37231 | 12/20 | 0.47 |
| ▸ | PPARD | Q03181 | 8/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517086 | 0.90 | PPARA (0.63) | PPARAPPARGPPARD | |
| SCHEMBL6531098 | 0.88 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6511476 | 0.88 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6511449 | 0.88 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL6512234 | 0.88 | PPARA (0.66) | PPARAPPARGPPARD | |
| SCHEMBL3285097 | 0.84 | PPARA (0.46) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL6511690 | 0.83 | PPARA (0.45) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL6512822 | 0.83 | PPARA (0.45) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL6510038 | 0.83 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL6509482 | 0.83 | PPARA (0.51) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | claimed |
| WO-2005080354-A1 | 1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS | PIERRE FABRE MEDICAMENT (FR) | 2005-09-01 | — | — | WO | disclosed |