Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | INPPL1 | O15357 | 8/20 | 0.36 |
| ▸ | INPP5A | Q14642 | 5/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | INPP5B | P32019 | 2/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7060762 | 0.88 | NR4A2 (0.33) | NR4A2GPR84 | |
| SCHEMBL29356973 | 0.84 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL23488 | 0.84 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL31324009 | 0.82 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL17668115 | 0.82 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL5058499 | 0.82 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| SCHEMBL29008754 | 0.82 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| Phosphoric Acid SCHEMBL8156858 | 0.82 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| Ammonia Solution, Strong SCHEMBL20492883 | 0.82 | HTR2A (0.40) | HTR2AHTR1AHTR2CHTR2BINPPL1 | |
| Inositol SCHEMBL2831131 | 0.79 | HTR2A (0.38) | HTR2AHTR1AHTR2CHTR2BINPPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050271667-A1 | Identification of a novel endothelial-derived gene EG-1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-12-08 | — | — | US | disclosed |
| US-20030129597-A1 | Identification of a novel endothelial-derived gene EG-1 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-07-10 | — | — | US | disclosed |
| EP-0651783-B1 | ALKALINE PHOSPHATASE ENZYME HAVING IMPROVED SPECIFIC ACTIVITY FOR USE IN INDICATOR REAGENTS | ABBOTT LAB (US) | 2003-05-28 | — | — | EP | disclosed |
| EP-0441252-B1 | Alkaline phosphatase enzymes having improved specific activity for use in indicator reagents | ABBOTT LAB (US) | 1997-09-03 | — | — | EP | disclosed |
| US-RE35585-E | DNA vector with isolated cDNA gene encoding metallopanstimulin | FERNANDEZ-POL JOSE A (US) | 1997-08-12 | — | — | US | disclosed |
| EP-0651783-A4 | ALKALINE PHOSPHATASE ENZYMES HAVING IMPROVED SPECIFIC ACTIVITY FOR USE IN INDICATOR REAGENTS. | ABBOTT LAB (US) | 1997-01-02 | — | — | EP | disclosed |
| US-5550214-A | ANTITUMOR AGENTS | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1995021862-A1 | ISOLATED ANTIGENIC ONCOGENE PEPTIDE FRAGMENTS AND USES | BRIGHAM AND WOMEN'S HOSPITAL (US) | 1995-08-17 | — | — | WO | disclosed |
| EP-0651783-A1 | ALKALINE PHOSPHATASE ENZYMES HAVING IMPROVED SPECIFIC ACTIVITY FOR USE IN INDICATOR REAGENTS | ABBOTT LABORATORIES (US) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994001531-A1 | ALKALINE PHOSPHATASE ENZYMES HAVING IMPROVED SPECIFIC ACTIVITY FOR USE IN INDICATOR REAGENTS | ABBOTT LABORATORIES (US) | 1994-01-20 | — | — | WO | disclosed |
| US-5243041-A | DNA vector with isolated CDNA gene encoding metallopanstimulin | THOMSON LICENSING S.A. (FR) | 1993-09-07 | — | — | US | disclosed |
| EP-0441252-A2 | Alkaline phosphatase enzymes having improved specific activity for use in indicator reagents | ABBOTT LABORATORIES (US) | 1991-08-14 | — | — | EP | disclosed |