SCHEMBL651311

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL651620	0.90	PTPN1 (0.42)	PTPN1CDC25BSMN1; SMN2PIM1GSK3B
	SCHEMBL651619	0.90	PTPN1 (0.42)	PTPN1CDC25BSMN1; SMN2PIM1GSK3B
	SCHEMBL651064	0.89	PIM1 (0.47)	PTPN1CDC25BPIM1GSK3BHPGD
	SCHEMBL650973	0.85	LMNA (0.39)	PTPN1CDC25BSMN1; SMN2PIM1GSK3B
	SCHEMBL10176414	0.85	HPGD (0.53)	PTPN1CDC25BGSK3BHPGDPOLB
	SCHEMBL651957	0.84	LMNA (0.41)	PTPN1CDC25BSMN1; SMN2GSK3BHPGD
	SCHEMBL651355	0.84	PTPN1 (0.46)	PTPN1CDC25BPIM1GSK3BHPGD
	SCHEMBL10176413	0.83	PTPN1 (0.44)	PTPN1CDC25BPIM1GSK3BHPGD
	SCHEMBL648559	0.83	SMN1; SMN2 (0.42)	PTPN1CDC25BSMN1; SMN2PIM1GSK3B
	SCHEMBL649069	0.82	PTPN1 (0.42)	PTPN1CDC25BPIM1GSK3BHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.