SCHEMBL651327

SCHEMBL651327

C=C(C)C(=O)OCCCCC(C)CCCCCC

nearest known ligand 0.77

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.77
ACE2 Q9BYF1 1/20 0.49
THRB P10828 1/20 0.46
NAAA Q02083 1/20 0.44
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
RAD52 P43351 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
EPHX1 P07099 1/20 0.42
FAAH O00519 2/20 0.42
ALDH1A1 P00352 1/20 0.40
ZDHHC7 Q9NXF8 1/20 0.40
CES2 O00748 1/20 0.40
HCAR2 Q8TDS4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL651728 1.00 TSHR (0.77) TSHRACE2THRBNAAAPOLB
SCHEMBL866131 1.00 TSHR (0.77) TSHRACE2THRBNAAAPOLB
SCHEMBL31180298 0.92 TSHR (0.71) TSHRACE2THRBNAAAPOLB
SCHEMBL11526952 0.92 TSHR (0.64) TSHRACE2THRBNAAAPOLB
SCHEMBL7736289 0.90 TSHR (0.77) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL9658227 0.90 TSHR (0.77) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL2912477 0.90 TSHR (0.77) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL31207506 0.90 TSHR (0.77) TSHRTHRBNAAAPOLBAPEX1
Isobutane SCHEMBL28087898 0.90 TSHR (0.89) TSHRTHRBNAAAPOLBAPEX1
SCHEMBL8169202 0.89 TSHR (0.80) TSHRTHRBNAAAPOLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4658738-A1 LOW VOLATILITY COMB POLYMER COMPOSITION FOR ENGINE OILS Evonik Operations GmbH (DE) 2025-12-10 EP disclosed
EP-4658739-A1 LOW VOLATILITY COMB POLYMER COMPOSITION FOR ENGINE OILS Evonik Operations GmbH (DE) 2025-12-10 EP disclosed
US-20250361408-A1 COATING SYSTEM AND COATED ARTICLE SHERWIN WILLIAMS GUANGDONG NEW MAT CO LTD (CN) 2025-11-27 US disclosed
EP-4646467-A1 TWO-COMPONENT COATING COMPOSITION, AND ARTICLE MADE THEREFROM Valspar Coatings (Shanghai) Co. Ltd. (CN) 2025-11-12 EP disclosed
US-12460104-B2 Two-component waterborne polyurethane coating composition and low gloss coating formed therefrom Sherwin-Williams (Guangdong) New Material Co., Ltd. (CN) 2025-11-04 US disclosed
WO-2025082420-A1 AQUEOUS EMULSION, METHOD FOR PREPARING THE SAME, COATING COMPOSITION AND ARTICLE GUANGDONG HUARUN PAINTS CO., LTD. (CN) 2025-04-24 WO disclosed
US-12168757-B2 Well defined low molecular weight dispersant polymethacrylates THE LUBRIZOL CORPORATION (US) 2024-12-17 US disclosed
US-12065526-B2 Process for the preparation of polyalkyl (meth)acrylate polymers EVONIK OPERATIONS GMBH (DE) 2024-08-20 US disclosed
WO-2024146484-A1 TWO-COMPONENT COATING COMPOSITION, AND ARTICLE MADE THEREFROM VALSPAR COATINGS (SHANGHAI) CO. LTD. (CN) 2024-07-11 WO disclosed
EP-4143279-B1 PROCESS FOR THE PREPARATION OF DISPERSANT POLYALKYL (METH)ACRYLATE POLYMERS EVONIK OPERATIONS GMBH (DE) 2024-06-26 EP disclosed
CN-101291988-A Transparent TPU (thermoplastic polyurethane)/PMMA (polymethyl (meth) acrylate) blends with improved impact resistance at low temperatures EVONIK ROEHM GMBH (DE) 2008-10-22 CN disclosed
US-20080132627-A1 Impact-Resistant Poly(Meth)Acrylate Moulding Masses With High Thermal Stability ROEHM GMBH (DE) 2008-06-05 US disclosed
CN-100376612-C Method for producing aqueous dispersions ROEHM GMBH (DE) 2008-03-26 CN disclosed
CN-101107311-A Impact-resistant poly(meth)acrylate moulding masses with high thermal stability ROEHM GMBH (DE) 2008-01-16 CN disclosed
CN-101087812-A Process for preparing polymers and compositions thereof LUBRIZOL CORP (US) 2007-12-12 CN disclosed
US-20060147714-A1 Core and shell particle for modifying impact resistance of a mouldable poly (meth) acrylate material ROEHM GMBH & CO. KG (DE) 2006-07-06 US disclosed
US-20060052515-A1 Process for producing aqueou dispersions ROEHM GMBH & CO. KG (DE) 2006-03-09 US disclosed
CN-1729219-A Process for preparing aqueous dispersions ROEHM GMBH (DE) 2006-02-01 CN disclosed
CN-1726238-A Core and shell particle for modifying impact resistance of a mouldable poly(meth)acrylate material ROEHM GMBH (DE) 2006-01-25 CN disclosed
CN-1589182-A Method for producing layers ROEHM GMBH (DE) 2005-03-02 CN disclosed