Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517605 | 0.82 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL6513288 | 0.73 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL6511366 | 0.72 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL5594600 | 0.72 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL5594125 | 0.71 | PTGS2 (0.88) | PTGS2PTGS1 | |
| SCHEMBL6516190 | 0.71 | PTGS2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL5594637 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5593984 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594391 | 0.70 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL5594727 | 0.70 | PTGS2 (0.76) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6949536-B2 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | PFIZER, INC. (US) | 2005-09-27 | — | — | US | disclosed |
| US-20040157824-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | PFIZER INC. | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157824-A1 | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents | CNR1, PTGS1, PTGER1 | PTGS2 29/4885PTGS1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.