SCHEMBL6513358

SCHEMBL6513358

C=C(Cl)C(=O)OC(=O)C(=C)CC

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1923846 0.87 ALDH1A1 (0.37) TDP1ALDH1A1TSHR
SCHEMBL8953258 0.85 ALDH1A1 (0.35) TDP1ALDH1A1TSHR
SCHEMBL28105202 0.83 TSHR (0.31) TDP1ALDH1A1TSHR
SCHEMBL506448 0.82 HSD17B10 (0.33) TDP1ALDH1A1
SCHEMBL1237423 0.78 ALDH1A1 (0.46) TDP1ALDH1A1TSHR
SCHEMBL997396 0.77 SOAT1 (0.38) TDP1ALDH1A1TSHR
SCHEMBL9722474 0.76 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL10527328 0.76 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL4200405 0.75
SCHEMBL375255 0.75 FFAR3 (0.38) TDP1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1270687-B1 Aqueous composite particle composition ROHM & HAAS (US) 2018-10-03 EP disclosed
US-6890983-B2 Aqueous composite particle composition ROHM AND HAAS COMPANY (US) 2005-05-10 US disclosed
US-20030045627-A1 Aqueous composite particle composition ROHM AND HAAS COMPANY 2003-03-06 US disclosed
EP-1270687-A2 Aqueous composite particle composition ROHM AND HAAS COMPANY (US) 2003-01-02 EP disclosed
EP-1209191-A2 Polymer-pigment composites ROHM AND HAAS COMPANY (US) 2002-05-29 EP disclosed