Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 12/20 | 0.58 |
| ▸ | ESR1 | P03372 | 11/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831992 | 0.81 | PTGS2 (0.80) | ESR2ESR1PTGS2MAPTSNCA | |
| SCHEMBL56593 | 0.78 | TOP2A (0.53) | MAPTTOP2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL31631310 | 0.78 | NPC1 (0.57) | MAPTTOP2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL29666387 | 0.76 | TOP2A (0.67) | PTGS2MAPTTOP2ARAB9ANPC1 | |
| SCHEMBL1378656 | 0.73 | ESR1 (1.00) | ESR2ESR1PTGS2MAPTSNCA | |
| SCHEMBL1376259 | 0.73 | ESR1 (1.00) | ESR2ESR1PTGS2MAPTSNCA | |
| SCHEMBL31154233 | 0.70 | NPC1 (0.49) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL25338158 | 0.69 | ESR1 (0.70) | ESR2ESR1PTGS2HSD17B1HSD17B2 | |
| SCHEMBL30791789 | 0.69 | ESR1 (0.70) | ESR2ESR1PTGS2HSD17B1HSD17B2 | |
| SCHEMBL27170092 | 0.69 | ESR1 (0.70) | ESR2ESR1PTGS2HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050080117-A1 | Substituted benzoxazoles as estrogenic agents | WYETH (US) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080117-A1 | Substituted benzoxazoles as estrogenic agents | ESR1, ESR2, ESRRA | ESR2 2/4885ESR1 1/4885PTGS2 2246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.