Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510945 | 0.90 | PPARG (0.34) | PPARGPPARA | |
| SCHEMBL6511007 | 0.88 | PPARG (0.35) | PPARGPPARA | |
| SCHEMBL6510392 | 0.84 | PPARG (0.31) | PPARGPPARA | |
| SCHEMBL6512345 | 0.84 | PPARG (0.31) | PPARGPPARA | |
| SCHEMBL6532884 | 0.84 | — | — | |
| SCHEMBL6511137 | 0.83 | PPARG (0.32) | PPARGPPARA | |
| SCHEMBL6279556 | 0.78 | — | — | |
| SCHEMBL6275498 | 0.77 | — | — | |
| SCHEMBL6275475 | 0.77 | PPARG (0.33) | PPARGPPARA | |
| SCHEMBL6281214 | 0.77 | PPARG (0.30) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005042509-A1 | 7-`(7-ALKOXY)-CHROM-3-EN-6-YL!-HEPTATRIENOIC ACID AND 7-`(3ALKOXY)-5,6-DIHYDRONAPHTHALEN-2-YL!-HEPTATRIENOIC ACID DERIVATIVES MODULATORS | ALLERGAN, INC. (US) | 2005-05-12 | — | — | WO | disclosed |