SCHEMBL6513846

SCHEMBL6513846

OC/C=C\c1ccccc1C(F)(F)F

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.58
MAOB P27338 9/20 0.49
BACE1 P56817 1/20 0.48
P4HB P07237 1/20 0.47
ABCG2 Q9UNQ0 1/20 0.47
GRIN2D O15399 2/20 0.45
GRIN3B O60391 2/20 0.45
GRIN1 Q05586 2/20 0.45
GRIN2A Q12879 2/20 0.45
GRIN2B Q13224 2/20 0.45
GRIN2C Q14957 2/20 0.45
GRIN3A Q8TCU5 2/20 0.45
MAOA P21397 1/20 0.44
MEN1 O00255 1/20 0.43
LMNA P02545 1/20 0.43
MAPT P10636 1/20 0.43
KMT2A Q03164 1/20 0.43
TNF P01375 2/20 0.40
RAB9A P51151 1/20 0.40
NOD1 Q9Y239 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL638979 1.00 NFKB1 (0.58) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL638980 1.00 NFKB1 (0.58) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL27298516 0.81 NFKB1 (0.53) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL29374535 0.81 NFKB1 (0.53) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL27532448 0.81 NFKB1 (0.53) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL2096074 0.81 NFKB1 (0.58) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL2096078 0.81 NFKB1 (0.58) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL256657 0.81 NFKB1 (0.53) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL27532447 0.81 NFKB1 (0.53) NFKB1MAOBBACE1P4HBABCG2
SCHEMBL27947936 0.80 NFKB1 (0.52) NFKB1MAOBBACE1P4HBABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2005015400-A TRIFLUOROMETHYLCINNAMYL ALCOHOL AND ITS MANUFACTURING METHOD CENTRAL GLASS CO LTD 2005-01-20 JP disclosed