Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28100998 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TSHR | |
| SCHEMBL93621 | 0.78 | — | — | |
| SCHEMBL11883827 | 0.78 | APP (0.44) | APP | |
| SCHEMBL2430307 | 0.77 | ALDH1A1 (0.59) | ALDH1A1TSHRFFAR1APP | |
| SCHEMBL29062047 | 0.76 | — | — | |
| SCHEMBL6317768 | 0.75 | ALDH1A1 (0.55) | ALDH1A1TSHRTDP1HDAC8 | |
| SCHEMBL6515287 | 0.74 | ALDH1A1 (0.41) | ALDH1A1TSHRFFAR1 | |
| SCHEMBL24384355 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1FFAR1HDAC8 | |
| SCHEMBL28331858 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TSHRTDP1FFAR1HDAC8 | |
| Water SCHEMBL20378930 | 0.72 | ALDH1A1 (0.92) | ALDH1A1TSHRTDP1HDAC8CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6944047-B2 | Variable-persistence molecular memory devices and methods of operation thereof | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-09-13 | — | — | US | claimed |
| US-20040120180-A1 | Variable-persistence molecular memory devices and methods of operation thereof | NORTH CAROLINA STATE UNIVERSITY | 2004-06-24 | — | — | US | claimed |
| US-6944047-B2 | Variable-persistence molecular memory devices and methods of operation thereof | NORTH CAROLINA STATE UNIVERSITY (US) | 2005-09-13 | — | — | US | disclosed |
| US-20040120180-A1 | Variable-persistence molecular memory devices and methods of operation thereof | NORTH CAROLINA STATE UNIVERSITY | 2004-06-24 | — | — | US | disclosed |