Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 8/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 4/20 | 0.54 |
| ▸ | PTPN12 | Q05209 | 4/20 | 0.54 |
| ▸ | PTPN22 | Q9Y2R2 | 4/20 | 0.54 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.54 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.53 |
| ▸ | AURKA | O14965 | 5/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.50 |
| ▸ | INCENP | Q9NQS7 | 4/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651435 | 1.00 | POLB (0.54) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL651137 | 0.92 | POLB (0.45) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL651131 | 0.92 | POLB (0.45) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL649726 | 0.90 | SYK (0.48) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL650807 | 0.90 | SYK (0.48) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL653261 | 0.90 | NPC1 (0.50) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL653260 | 0.90 | NPC1 (0.50) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL649045 | 0.90 | MEN1 (0.46) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL649044 | 0.90 | MEN1 (0.46) | POLBPTPN7DUSP3PTPN12PTPN22 | |
| SCHEMBL653119 | 0.89 | MAPT (0.52) | POLBPTPN7DUSP3PTPN12PTPN22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119812-B2 | Thiazolidinone derivative | SBI BIOTECH CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | SBI BIOTECH CO., LTD. (JP) | 2011-08-04 | — | — | US | disclosed |
| WO-2010122979-A1 | THIAZOLIDINONE DERIVATIVE | ＳＢＩバイオテック株式会社 (JP) | 2010-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190299-A1 | THIAZOLIDINONE DERIVATIVE | CDC7, CDK17, CDCA2 | POLB 2967/4885PTPN7 437/4885DUSP3 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.