SCHEMBL653119

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL653120	1.00	MAPT (0.52)	MAPTMEN1KMT2APOLBHPGD
	SCHEMBL649726	0.90	SYK (0.48)	MAPTMEN1KMT2APOLBMAPK1
	SCHEMBL650807	0.90	SYK (0.48)	MAPTMEN1KMT2APOLBMAPK1
	SCHEMBL653260	0.89	NPC1 (0.50)	MAPTMEN1KMT2APOLBPTPN7
	SCHEMBL653261	0.89	NPC1 (0.50)	MAPTMEN1KMT2APOLBPTPN7
	SCHEMBL651435	0.89	POLB (0.54)	MAPTMEN1KMT2APOLBHPGD
	SCHEMBL651434	0.89	POLB (0.54)	MAPTMEN1KMT2APOLBHPGD
	SCHEMBL649044	0.89	MEN1 (0.46)	MAPTMEN1KMT2APOLBHPGD
	SCHEMBL649045	0.89	MEN1 (0.46)	MAPTMEN1KMT2APOLBHPGD
	SCHEMBL653571	0.88	MEN1 (0.42)	MAPTMEN1KMT2APOLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.