SCHEMBL651478

SCHEMBL651478

C=C(C)C(=O)OCC(O)COC(C)C

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.60
THRB P10828 1/20 0.39
ALDH1A1 P00352 3/20 0.37
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
HPGD P15428 3/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NR2E1 Q9Y466 1/20 0.33
HTT P42858 1/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
USP2 O75604 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9305819 0.89 TSHR (0.60) TSHRTHRBALDH1A1HPGDSMN1; SMN2
SCHEMBL94906 0.88 TSHR (0.68) TSHRTHRBALDH1A1HPGDSMN1; SMN2
SCHEMBL19998240 0.86 TSHR (0.65) TSHRTHRBALDH1A1HPGDSMN1; SMN2
SCHEMBL13758492 0.85 TSHR (0.55) TSHRTHRBALDH1A1HPGDSMN1; SMN2
SCHEMBL9173095 0.84 TSHR (0.55) TSHRTHRBALDH1A1
SCHEMBL20029770 0.83 TSHR (0.62) TSHRTHRBALDH1A1HPGDSMN1; SMN2
SCHEMBL12163040 0.83 TSHR (0.62) TSHRTHRBALDH1A1HPGDSMN1; SMN2
SCHEMBL996250 0.83 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL347487 0.82 TSHR (0.61) TSHRTHRBALDH1A1HPGDSMN1; SMN2
SCHEMBL3412123 0.82 TSHR (0.61) TSHRTHRBALDH1A1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210163650-A1 POLYMER MATERIAL MENICON CO., LTD. (JP) 2021-06-03 US disclosed
EP-3822296-A1 POLYMER MATERIAL Menicon Co., Ltd. (JP) 2021-05-19 EP disclosed
EP-2735444-A2 Lithographic printing plate precursor for newspaper printing and method for producing the same, and plate making method of lithographic printing plate FUJIFILM Corporation (JP) 2014-05-28 EP disclosed
US-8119327-B2 Hard, cold flowable, photosensitive photoresist coatings; consistant flexibility; strippability; shelf life; prepolymers comprised of such as methyl methacrylate, benzyl methacrylate and glycidyl methacrylate; photocuring with diacrylate monomer or oligimer HUNTSMAN ADVANCED MATERIALS AMERICAS LLC (US) 2012-02-21 US disclosed
EP-1487888-B1 POLYMERISABLE COMPOSITION HUNTSMAN ADV MAT SWITZERLAND (CH) 2008-10-22 EP disclosed
CN-1294167-C Polymerisable composition HUNTSMAN ADV MAT AMERICAS INC (CH) 2007-01-10 CN disclosed
US-20050170094-A1 Polymerisable composition HUNTSMAN ADVANCED MATERIALS AMERICAS INC 2005-08-04 US disclosed
CN-1643007-A Polymerisable composition HUNTSMAN ADV MAT AMERICAS INC (CH) 2005-07-20 CN disclosed
EP-1487888-A2 POLYMERISABLE COMPOSITION Huntsman Advanced Materials (Switzerland) GmbH (CH) 2004-12-22 EP disclosed
WO-2003082937-A2 POLYMERISABLE COMPOSITION HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) 2003-10-09 WO disclosed