Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL651478 | 0.89 | TSHR (0.60) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL94906 | 0.88 | TSHR (0.68) | TSHRTHRBALDH1A1TDP1USP2 | |
| SCHEMBL19998240 | 0.86 | TSHR (0.65) | TSHRTHRBALDH1A1TDP1USP2 | |
| SCHEMBL13758492 | 0.85 | TSHR (0.55) | TSHRTHRBALDH1A1USP2CYP3A4 | |
| SCHEMBL18660130 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1 | |
| SCHEMBL9173095 | 0.84 | TSHR (0.55) | TSHRTHRBALDH1A1TDP1 | |
| SCHEMBL7032296 | 0.84 | TSHR (0.50) | TSHRTHRBALDH1A1 | |
| SCHEMBL7867266 | 0.84 | ALDH1A1 (0.57) | TSHRALDH1A1CYP3A4 | |
| SCHEMBL20029770 | 0.83 | TSHR (0.62) | TSHRTHRBALDH1A1TDP1USP2 | |
| SCHEMBL12163040 | 0.83 | TSHR (0.62) | TSHRTHRBALDH1A1TDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023182241-A1 | COMPOSITION FOR DENTAL MATERIAL AND DENTAL MATERIAL | 三井化学株式会社 | 2023-09-28 | — | — | WO | disclosed |
| WO-2023106419-A1 | DENTAL CURABLE COMPOSITION | クラレノリタケデンタル株式会社 | 2023-06-15 | — | — | WO | disclosed |
| US-5302630-A | Good bonding strength and waterproofing using a polymer of a carboxy and anhydride-free acrylic ester, a vinylsilane and an unsaturated compound and a peroxy compound and redox system | MITSUBISHI RAYON CO., LTD. (JP) | 1994-04-12 | — | — | US | disclosed |
| EP-0413174-B1 | DENTAL ADHESIVE COMPOSITION | MITSUBISHI RAYON CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |