⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3067451 | 0.79 | — | — | |
| SCHEMBL29127476 | 0.72 | — | — | |
| SCHEMBL6317830 | 0.70 | — | — | |
| SCHEMBL2182873 | 0.67 | — | — | |
| SCHEMBL2345872 | 0.67 | — | — | |
| SCHEMBL3070073 | 0.65 | FDPS (0.39) | — | |
| SCHEMBL28732365 | 0.63 | — | — | |
| SCHEMBL3943616 | 0.61 | — | — | |
| SCHEMBL333912 | 0.61 | — | — | |
| SCHEMBL1776917 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102458418-B | Pharmaceutical application of oligonucleotide compound | QUARK PHARMACEUTICALS, INC. (US) | 2015-09-16 | — | — | CN | disclosed |
| CN-102458418-A | Method for treating chronic kidney disease | QUARK PHARMACEUTICALS INC | 2012-05-16 | — | — | CN | disclosed |
| US-20050059815-A1 | Processes for the synthesis of 2'-O-substituted pyrimidines and oligomeric compounds therefrom | COOK PHILLIP DAN (US) | 2005-03-17 | — | — | US | disclosed |