Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 16/20 | 0.40 |
| ▸ | HTR1D | P28221 | 15/20 | 0.40 |
| ▸ | HTR1B | P28222 | 14/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4174721 | 0.86 | HTR1D (0.53) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL4173595 | 0.79 | HTR1D (0.53) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL4177900 | 0.71 | HTR1A (0.71) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL2304612 | 0.71 | HTR1A (0.72) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL2307450 | 0.71 | HTR1A (0.71) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL4167412 | 0.70 | HTR1A (0.71) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL4170651 | 0.70 | HTR1A (0.71) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL4169062 | 0.69 | HTR1A (0.59) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL4183122 | 0.69 | HTR1D (0.63) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| Hydrochloric Acid SCHEMBL4185460 | 0.69 | HTR1A (0.58) | HTR1AHTR1DHTR1BSLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562917-A1 | BENZOXAZINONE DERIVATIVES, PREPARATION THEREOF AND USES IN THE TREATMENT OF CNS AND OTHER DISORDERS | GLAXO GROUP LIMITED (GB) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046124-A1 | BENZOXAZINONE DERIVATIVES, PREPARATION THEREOF AND USES IN THE TREATMENT OF CNS AND OTHER DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-06-03 | — | — | WO | disclosed |