Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | BID | P55957 | 7/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 7/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 6/20 | 0.39 |
| ▸ | BAK1 | Q16611 | 6/20 | 0.39 |
| ▸ | F7 | P08709 | 3/20 | 0.39 |
| ▸ | F3 | P13726 | 3/20 | 0.39 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ECE1 | P42892 | 1/20 | 0.39 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8654059 | 0.81 | HMGB1 (0.42) | KAT8EP300KAT2BKAT5KDM4E | |
| SCHEMBL6509418 | 0.81 | KAT8 (0.56) | KAT8EP300KAT2BKAT5KDM4E | |
| SCHEMBL2778138 | 0.80 | BID (0.38) | KAT8EP300KAT2BKAT5KDM4E | |
| SCHEMBL6566933 | 0.80 | BID (0.55) | KAT8EP300KAT2BKAT5KDM4E | |
| SCHEMBL8654089 | 0.80 | HMGB1 (0.41) | KAT8EP300KAT2BKAT5KDM4E | |
| SCHEMBL6567329 | 0.80 | HMGB1 (0.41) | KAT8EP300KAT2BKAT5KDM4E | |
| SCHEMBL8654374 | 0.80 | HMGB1 (0.41) | KAT8EP300KAT2BKAT5KDM4E | |
| SCHEMBL8654727 | 0.80 | HMGB1 (0.41) | KAT8EP300KAT2BKAT5KDM4E | |
| SCHEMBL7870129 | 0.80 | GABRA1 (0.44) | KDM4EMAPTHSD17B10PARP1ALDH1A1 | |
| SCHEMBL1538231 | 0.79 | KAT8 (0.59) | KAT8EP300KAT2BKAT5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005105820-A2 | MACROCYCLIC CADMIUM COMPLEXES | UNIVERSITY OF EAST ANGLIA (GB) | 2005-11-10 | — | — | WO | disclosed |