SCHEMBL6515640 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MEN1	O00255	3/20	0.37

▸	KMT2A	Q03164	3/20	0.37

▸	TP53	P04637	2/20	0.36

▸	LMNA	P02545	1/20	0.36

▸	ADORA3	P0DMS8	3/20	0.36

▸	ADORA1	P30542	6/20	0.35

▸	ADORA2A	P29274	2/20	0.34

▸	FAAH	O00519	1/20	0.34

▸	CHRNA7	P36544	1/20	0.34

▸	PPARA	Q07869	1/20	0.34

▸	USP2	O75604	1/20	0.34

▸	ALDH1A1	P00352	1/20	0.34

▸	TSHR	P16473	1/20	0.34

▸	SMN1; SMN2	Q16637	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6515691	0.89	PPARA (0.31)	ADORA3PPARA
SCHEMBL6515694	0.89	PPARA (0.31)	ADORA3PPARA
SCHEMBL6509723	0.85	PPARA (0.50)	FAAHPPARA
SCHEMBL6512124	0.83	PPARA (0.51)	FAAHPPARA
SCHEMBL6511112	0.83	PPARA (0.42)	MEN1KMT2ATP53LMNAPPARA
SCHEMBL6512146	0.82	PPARA (0.49)	PPARA
SCHEMBL6508401	0.80	PPARA (0.49)	FAAHPPARA
SCHEMBL6508372	0.79	PPARA (0.51)	PPARA
SCHEMBL6513188	0.79	PPARA (0.51)	PPARA
SCHEMBL3284363	0.79	PPARA (0.40)	MEN1KMT2ATP53ADORA3PPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2005080354-A1	1,2,4-TRIAZINES DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN HUMAN THERAPEUTICS	PIERRE FABRE MEDICAMENT (FR)	2005-09-01	—	—	WO	disclosed