Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 20/20 | 1.00 |
| ▸ | HTR1D | P28221 | 20/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 20/20 | 1.00 |
| ▸ | HTR1B | P28222 | 18/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 18/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4174506 | 1.00 | HTR1A (1.00) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| SCHEMBL4179650 | 1.00 | HTR1A (1.00) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| Hydrochloric Acid SCHEMBL4176346 | 0.99 | HTR1A (0.98) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| SCHEMBL4182250 | 0.86 | HTR1D (1.00) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| Hydrochloric Acid SCHEMBL4182287 | 0.85 | HTR1D (0.98) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| SCHEMBL10212145 | 0.84 | HTR1A (0.76) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| Hydrochloric Acid SCHEMBL431744 | 0.84 | HTR1A (0.75) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| SCHEMBL10212447 | 0.84 | HTR1A (0.77) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| Hydrochloric Acid SCHEMBL432604 | 0.83 | HTR1A (0.75) | HTR1AHTR1DSLC6A4HTR1BKCNH2 | |
| SCHEMBL430808 | 0.82 | HTR1A (0.70) | HTR1AHTR1DSLC6A4HTR1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1562917-A1 | BENZOXAZINONE DERIVATIVES, PREPARATION THEREOF AND USES IN THE TREATMENT OF CNS AND OTHER DISORDERS | GLAXO GROUP LIMITED (GB) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004046124-A1 | BENZOXAZINONE DERIVATIVES, PREPARATION THEREOF AND USES IN THE TREATMENT OF CNS AND OTHER DISORDERS | GLAXO GROUP LIMITED (GB) | 2004-06-03 | — | — | WO | disclosed |