Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 17/20 | 0.65 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.65 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.65 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6511803 | 0.90 | HDAC6 (0.69) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL8288510 | 0.81 | HDAC6 (0.55) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL21975920 | 0.81 | HDAC6 (0.95) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL6513390 | 0.80 | HDAC1 (0.79) | HDAC6HDAC1HDAC8 | |
| SCHEMBL6513395 | 0.80 | HDAC1 (0.79) | HDAC6HDAC1HDAC8 | |
| SCHEMBL6513385 | 0.80 | HDAC1 (0.79) | HDAC6HDAC1HDAC8 | |
| SCHEMBL18229537 | 0.79 | HDAC6 (1.00) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL2116566 | 0.77 | HDAC6 (0.56) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL18229519 | 0.74 | HDAC6 (1.00) | HDAC6HDAC1HDAC8HDAC3HDAC2 | |
| SCHEMBL6507848 | 0.73 | HDAC6 (0.65) | HDAC6HDAC1HDAC8HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066151-A2 | HISTONE DEACETYLASE INHIBITORS | TAKEDA SAN DIEGO, INC. (US) | 2005-07-21 | — | — | WO | claimed |
| US-20050137234-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2005-06-23 | — | — | US | claimed |
| US-20050137234-A1 | Histone deacetylase inhibitors | SYRRX, INC. | 2005-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050137234-A1 | Histone deacetylase inhibitors | HDAC1, HDAC5, HDAC11 | HDAC6 10/4885HDAC1 1/4885HDAC8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.