SCHEMBL6516435

SCHEMBL6516435

CC(=O)c1ccc(S)c(C(=O)O)c1.[NaH]

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 19/20 0.51
AKR1C2 P52895 19/20 0.51
AKR1B10 O60218 2/20 0.49
AKR1B1 P15121 2/20 0.49
AKR1C4 P17516 2/20 0.49
AKR1C1 Q04828 2/20 0.49
MAPT P10636 1/20 0.45
HDAC8 Q9BY41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3183610 0.98 AKR1C3 (0.53) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL6520256 0.96 AKR1C3 (0.51) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL6516443 0.96 AKR1C3 (0.51) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL5227394 0.86 MAPT (0.54) MAPTHDAC8
SCHEMBL7262775 0.84 AKR1C3 (0.44) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL6513118 0.83 AKR1C3 (0.39) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL6511440 0.83 NOS3 (0.40) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL5798910 0.82 AKR1C3 (0.51) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL6511217 0.81 NOS3 (0.41) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4
SCHEMBL6516108 0.81 AKR1C3 (0.40) AKR1C3AKR1C2AKR1B10AKR1B1AKR1C4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2656882-B1 Golf ball SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3292893-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2021-06-09 EP disclosed
EP-3156441-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-25 EP disclosed
EP-3329971-B1 GOLF BALL SUMITOMO RUBBER IND (JP) 2020-11-18 EP disclosed
EP-2666521-B1 Golf ball SUMITOMO RUBBER IND (JP) 2020-09-02 EP disclosed
EP-2669326-B1 Golf ball SUMITOMO RUBBER IND (JP) 2019-06-12 EP disclosed
US-10286258-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-05-14 US disclosed
US-10272296-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-30 US disclosed
US-10265585-B2 Golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-04-23 US disclosed
EP-3329971-A1 GOLF BALL Dunlop Sports Co., Ltd. (JP) 2018-06-06 EP disclosed
US-20130005506-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005508-A1 GOLF BALL DUNLOP SPORTS CO. LTD. (JP) 2013-01-03 US disclosed
US-20130005507-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20130005505-A1 GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-01-03 US disclosed
US-20120172150-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120172149-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-07-05 US disclosed
US-20120142453-A1 GOLF BALL SRI SPORTS LIMITED (JP) 2012-06-07 US disclosed
US-6919393-B2 Solid golf ball SRI SPORTS LIMITED (JP) 2005-07-19 US disclosed
US-20030144425-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed
US-20030144427-A1 Solid golf ball SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2003-07-31 US disclosed