Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28687491 | 0.81 | ALDH1A1 (0.37) | ALDH1A1TDP1GAAMGAMSI | |
| SCHEMBL6599659 | 0.81 | ALDH1A1 (0.42) | ALDH1A1HSD17B10LMNATDP1ALOX15 | |
| SCHEMBL27503341 | 0.79 | ALDH1A1 (0.41) | ALDH1A1HSD17B10LMNATDP1ALOX15 | |
| SCHEMBL315047 | 0.78 | ALDH1A1 (0.40) | ALDH1A1HSD17B10LMNAALOX15GAA | |
| SCHEMBL28160177 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HSD17B10LMNATDP1ALOX15 | |
| Ammonia Solution, Strong SCHEMBL1725012 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HSD17B10LMNAALOX15GAA | |
| SCHEMBL5317054 | 0.75 | ALDH1A1 (0.37) | ALDH1A1HSD17B10LMNATDP1ALOX15 | |
| SCHEMBL9781578 | 0.75 | ALDH1A1 (0.43) | ALDH1A1TDP1TRPA1CYP2C9 | |
| SCHEMBL29055376 | 0.73 | ALDH1A1 (0.39) | ALDH1A1HSD17B10LMNATDP1ALOX15 | |
| SCHEMBL10848782 | 0.73 | ALDH1A1 (0.42) | ALDH1A1LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050277766-A1 | Udp-glucose aglycon-glucosytransferase | MOLLER, BIRGER LINDBERG (DK) | 2005-12-15 | — | — | US | disclosed |
| US-4677131-A | Cyclic ureas as dermal penetration enhancers | MERCK & CO., INC. (US) | 1987-06-30 | — | — | US | disclosed |
| EP-0222664-A2 | Novel cyclic ureas as dermal penetration enhancers | MERCK & CO. INC. (US) | 1987-05-20 | — | — | EP | disclosed |
| EP-0052991-B1 | CARBOXYALKYL AMINO ACID DERIVATIVES OF VARIOUS SUBSTITUTED PROLINES | E.R. Squibb & Sons, Inc. (US) | 1987-02-04 | — | — | EP | disclosed |
| US-4462943-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1984-07-31 | — | — | US | disclosed |