SCHEMBL651674

SCHEMBL651674

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nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.32
TSHR P16473 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21082001 0.94 ATM (0.33) ATMTSHRHCAR2
SCHEMBL997670 0.92 GSTP1 (0.33) ATMTSHR
SCHEMBL19834168 0.88 KDM4E (0.32)
SCHEMBL5535259 0.86 TSHR (0.35) ATMTSHRHCAR2
SCHEMBL347488 0.86 TSHR (0.35) ATMTSHRHCAR2
SCHEMBL996251 0.82 TDP1 (0.38) TSHR
SCHEMBL7030841 0.81 HCAR2 (0.37) ATMTSHRHCAR2
SCHEMBL20335453 0.80 TSHR (0.39) ATMTSHRHCAR2
SCHEMBL28138681 0.80 HSD17B10 (0.42) ATMHCAR2
SCHEMBL2866953 0.80 HSD17B10 (0.38) TSHRHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11504448-B2 High-impact, transparent prosthesis material having a low residual MMA content KULZER GMBH (DE) 2022-11-22 US disclosed
EP-3164097-B1 MILL BLANKS BASED ON A POLYMERIZED, FRACTURE-TOUGH PROSTHESIS MATERIAL KULZER & CO GMBH (DE) 2022-05-11 EP disclosed
US-11007302-B2 Auto-polymerizable prosthetic material and polymerized, fracture-tough prosthetic material with increased colour stability KULZER GMBH (DE) 2021-05-18 US disclosed
US-20200289705-A1 HIGH-IMPACT, TRANSPARENT PROSTHESIS MATERIAL HAVING A LOW RESIDUAL MMA CONTENT KULZER GMBH (DE) 2020-09-17 US disclosed
EP-3373991-B1 HIGH-IMPACT, TRANSPARENT PROSTHESIS MATERIAL HAVING A LOW RESIDUAL MMA CONTENT KULZER & CO GMBH (DE) 2020-07-01 EP disclosed
US-20200071513-A1 Curable (meth)acrylic resin compositions having enhanced viscosity RÖHM GMBH (DE) 2020-03-05 US disclosed
EP-2529762-B1 PROSTHETIC BASE MATERIAL THAT IS BREAK-RESISTANT AFTER HARDENING, DERIVED FROM AUTOPOLYMERISING OR COLD POLYMERISING COMPOUNDS KULZER & CO GMBH (DE) 2019-10-16 EP disclosed
US-10420712-B2 Mill blanks based on a polymerized, fracture-tough prosthesis material HERAEUS KULZER GMBH (DE) 2019-09-24 US disclosed
US-10358552-B2 Impact-resistant molding material having an improved characteristics profile EVONIK RÖHM GMBH (DE) 2019-07-23 US disclosed
EP-3369787-B1 CURABLE (METH)ACRYLIC RESIN COMPOSITIONS HAVING ENHANCED VISCOSITY EVONIK ROEHM GMBH (DE) 2019-05-08 EP disclosed
US-5408022-A Useful for dental materials, non-releasing antimicrobial polymer; addition polymers KURARAY CO., LTD. (JP) 1995-04-18 US disclosed
US-5350782-A Mixture of inorganic oxide particles of two sizes, addition polymerizable monomer KANEBO, LTD. (JP) 1994-09-27 US disclosed
US-5321053-A Curable mixture of vinyl monomer containing acidic group and photoinitiator KURARAY CO., LTD. (JP) 1994-06-14 US disclosed
EP-0537774-A1 Antimicrobial polymerizable composition, the polymer and article obtained from the same KURARAY CO., LTD. (JP) 1993-04-21 EP disclosed
EP-0530926-A1 Dental filling composition KANEBO LTD. (JP) 1993-03-10 EP disclosed
EP-0155812-B1 DENTAL COMPOSITIONS KURARAY CO., LTD. (JP) 1991-09-11 EP disclosed
EP-0150952-B1 PHOTOPOLYMERIZABLE COMPOSITION KURARAY CO., LTD. (JP) 1989-08-30 EP disclosed
US-4668712-A MONOMER, PHOTOINITIATOR, DENTAL FILLINGS KURARAY CO., LTD. (JP) 1987-05-26 US disclosed
EP-0150952-A2 Photopolymerizable composition KURARAY CO., LTD. (JP) 1985-08-07 EP disclosed
US-4302381-A Dental material KURARAY CO., LTD. (JP) 1981-11-24 US disclosed